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新生儿特别护理及孵育器相关背景知识--英文

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郑振寰 发表于 2010-3-4 12:42 | 显示全部楼层 |阅读模式

Neonatal intensive-care unit

A newborn infant sleeping in an incubator.

A neonatal intensive care unit, usually shortened NICU (sometimes pronounced "Nickyou") and also called a newborn intensive care unit, intensive care nursery (ICN), and special care baby unit (SCBU [pronounced "Skiboo"], especially in Great Britain), is a unit of a hospital specializing in the care of ill or premature newborn infants. The NICU is distinct from a special care nursery (SCN) in providing a high level of intensive care to premature infants while the SCN provides specialized care for infants with less severe medical problems.

NICUs were developed in the 1950s and 1960s by pediatricians to provide better temperature support, isolation from infection risk, specialized feeding, and greater access to specialized equipment and resources. Infants are cared for in incubators or "open warmers." Some low birth weight infants need respiratory support ranging from extra oxygen (by head hood or nasal cannula) to continuous positive airway pressure (CPAP) or mechanical ventilation. Public access is limited, and staff and visitors are required to take precautions to reduce transmission of infection. Nearly all children's hospitals have NICUs, but they can often be found in large general hospitals as well.

A NICU is typically directed by one or more neonatologists and staffed by nurses, nurse practitioners, Nursery Nurses, physician assistants, resident physicians, and respiratory therapists. Many other ancillary services are necessary for a top-level NICU. Other physicians, especially those with "organ-defined" specialties often assist in the care of these infants.

Contents

 
  • 1 Early years
    • 1.1 Increasing technology
    • 1.2 Changing priorities
  • 2 See also
  • 3 External links

 Early years

Doctors took an increasing role in childbirth from the eighteenth century onwards. However, the care of newborn babies, sick or well, remained largely in the hands of mothers and midwives. Some baby incubators, similar to those used for hatching chicks, were devised in the late nineteenth century. In the United States these were shown at commercial exhibitions, complete with babies inside, until 1943. It wasn't until after the Second World War that special care baby units (SCBUs) were established in many hospitals. In Britain, early SCBUs opened in Birmingham and Bristol. At Southmead Hospital, Bristol, initial opposition from obstetricians lessened after quadruplets born there in 1948 were successfully cared for in the new unit. More resources became available - the first unit had been set up with £100. Most early units had little equipment and relied on careful nursing and observation.

Incubators were expensive so the whole room often was kept warm instead. Cross-infection between babies was greatly feared. Strict nursing routines involved staff wearing gowns and masks, constant hand washing and minimal handling of babies. Parents were sometimes allowed to watch through the windows of the unit. Much was learned about feeding - frequent, tiny feeds seemed best - and breathing. Oxygen was given freely until the end of the 1950s, when it was shown that the high concentrations reached inside incubators caused some babies to go blind. Monitoring conditions in the incubator, and the baby itself, was to become a major area of research. Although incubators provided oxygen and warmth, science in the 1950s was limited and it was not until later that technology played a larger role in the decline of infant mortality. Even though the elimination of infectious disease was mostly responsible for decline in infant mortality, low birth weight infant mortality remained high. Yet, because of medical advances in neonatology, low birth weight infants today are surviving on average 15 years more than low weight infants born in the 1950s.

 Increasing technology

Neonatal intensive care unit from 1980

By the 1970s SCBUs were an established part of hospitals in the developed world. In Britain, some early units ran community programmes, sending experienced nurses to help care for premature babies at home. But increasingly technological monitoring and therapy meant special care for babies became hospital-based. By the 1980s, over 90% of births took place in hospital anyway. The emergency dash from home to SCBU with baby in a transport incubator had become a thing of the past, though transport incubators were still needed. Specialist equipment and expertise were not available at every hospital, and strong arguments were made for large, centralised SCBUs. On the downside was the long travelling time for frail babies and for parents. A 1979 study showed that 20% of babies in SCBUs for up to a week were never visited by either parent. Centralised or not, by the 1980s few questioned the role of SCBUs in saving babies. Around 80% of babies born weighing under 1.5 kg now survived, compared to around 40% in the 1960s. From 1982 in Britain pediatricians could train and qualify in the sub-specialty of neonatal medicine.

Neonatal intensive care unit in 2009.

Not only careful nursing, but also new techniques and instruments now played a major role. As in adult intensive care units, the use of monitoring and life support systems became routine. These needed special modification for small babies, whose bodies were tiny and often immature. Adult ventilators, for example, could damage babies lungs and gentler techniques with smaller pressure changes were devised. The many tubes and sensors used for monitoring the baby's condition, blood sampling and artificial feeding made some babies scarcely visible beneath the technology. Furthermore, by 1975, over 18% of newborn babies in Britain were being admitted to SCBUs. Some hospitals admitted all babies delivered by Caesarian section, or under 2500g in weight. The fact that these babies missed early close contact with their mothers was a growing concern. As in other area of medicine, the 1980s saw questions being raised about the human, and the economic costs of too much technology. Admission policies gradually changed. In addition, treating low birth weight infants is expensive, especially when there are much cheaper ways of ensuring healthy babies. The key is prevention. Money can be spent on programs educating mothers on staying healthy during their pregnancy. One program (one that encourages women to stop smoking) is one third the price of neonatal intensive care and has been proven to work. During this program, a significant number of women often quit.

 Changing priorities

SCBUs now concentrate on treating very small, premature, or otherwise sick babies. Some of these babies are from higher-order multiple births, but most are still single babies born too early. Premature labour, and how to prevent it, remains a perplexing problem for doctors. Even though medical advancements allow doctors to save low birth weight babies, it ostensibly better to prevent such births from happening in the first place.

A new mother holds her premature baby at Kapiolani Medical Center NICU in Honolulu, Hawaii

Over the last 10 years or so, SCBUs have become much more 'parent friendly', encouraging maximum involvement with the babies. Routine gowns and masks have gone and parents are encouraged to help with care as much as possible. Cuddling, and skin-to-skin contact, also known as Kangaroo care, are seen as beneficial for all but the frailest (very tiny babies are exhausted by the stimulus of being handled, or larger critically ill infants). Less stressful ways of delivering high-technology medicine to tiny patients have been devised - stick-on sensors to measure blood oxygen levels through the skin, for example, and ways of reducing the amount of blood taken for tests.

Some major problems of the SCBU have almost disappeared. Exchange transfusions, in which all the blood is removed and replaced, little by little, are rare now. Rhesus incompatibility (a difference in blood groups) between mother and baby is largely preventable. Breathing difficulties and brain hemorrhage still claim many infant lives and are the focus of many current research projects.

The long term outlook for premature babies saved by SCBUs has always been a concern. From the early years, it was reported that a higher proportion than normal grew up with disabilities, including cerebral palsy and learning difficulties. Now that treatments are available for many of the problems faced by tiny or immature babies in the first weeks of life, long-term follow-up, and minimising long-term disability, are major research areas.

Besides prematurity and extreme low birth weight, common diseases cared for in a NICU include perinatal asphyxia, extreme cases of preeclampsia/eclampsia, major birth defects, sepsis, neonatal jaundice, and respiratory distress syndrome due to immaturity of the lungs. Complications of extreme prematurity may include intracranial hemorrhage, chronic bronchopulmonary dysplasia (see Infant respiratory distress syndrome), or retinopathy of prematurity. An infant may spend a day of observation in a NICU or may spend many months there.

Neonatology and NICUs have greatly increased the survival of very low birth weight and extremely premature infants. In the era before NICUs, infants of birth weight less than 1400 grams (3 lb, usually about 30 weeks gestation) rarely survived. Today, infants of 500 grams at 26 weeks have a fair chance of survival.

The NICU environment provides challenges as well as benefits. Stressors for the infants can include continual light, a high level of noise, separation from their mothers, reduced physical contact, painful procedures, and interference with the opportunity to breastfeed. A NICU can be stressful for the staff as well. A special aspect of NICU stress for both parents and staff is that infants may survive, but with damage to the brain or eyes.[citation needed]

NICU rotations are essential aspects of pediatric and obstetric residency programs, but NICU experience is encouraged by other specialty residencies, such as family practice, surgery, Pharmacy, and emergency medicine.

 See also

  • Intensive Care Unit
  • Neonatology
  • Pediatric intensive care unit
  • Embrace (incubator)

 External links

  • Life in the NICU: what parents can expect
  • Equipment used in the NICU -- interactive parent friendly information

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 楼主| 郑振寰 发表于 2010-3-4 12:43 | 显示全部楼层

Neonatology

Physician performing a physical exam on a newborn baby after a Caesarean section.

Neonatology is a subspecialty of pediatrics that consists of the medical care of newborn infants, especially the ill or premature newborn infant. It is a hospital-based specialty, and is usually practiced in neonatal intensive care units (NICUs). The principal patients of neonatologists are newborn infants who are ill or requiring special medical care due to prematurity, low birth weight, intrauterine growth retardation, congenital malformations (birth defects), sepsis, or birth asphyxias.

Contents

 
  • 1 History
  • 2 Academic training
  • 3 Spectrum of care
  • 4 References

 History

While high infant mortality rates were recognized by the British medical community at least as early as the 1860s,[1] modern neonatal intensive care is a relatively recent advance. In 1898 Dr. Joseph B. De Lee established the first premature infant incubator station in Chicago, Illinois. The first American textbook on prematurity was published in 1922. In 1952 Dr. Virginia Apgar described the APGAR score scoring system as a means of evaluating a newborn's condition. It was not until 1965 that the first American newborn intensive care unit (NICU) was opened in New Haven, Connecticut and in 1975 the American Board of Pediatrics established sub-board certification for neonatology.[2]

The 1960s brought a rapid escalation in neonatal services with the advent of mechanical ventilation of the newborn. This allowed for survival of smaller and smaller newborns. In the 1980s, the development of pulmonary surfactant replacement therapy further improved survival of extremely premature infants and decreased chronic lung disease, one of the complications of mechanical ventilation, among less severely premature survivors. In 2006 newborns as small as 450 grams and as early as 22 weeks gestation have a tiny chance of survival. In modern NICUs, infants weighing 1000 grams and at 27 weeks gestation have an approximately 90% chance of survival and the majority have normal neurological development.[3]

 Academic training

A neonatologist is a physician practicing neonatology, holding either an M.D. (Doctor of Medicine) or D.O. (Doctor of Osteopathic Medicine) degree. To become a neonatologist, the physician initially receives training as a pediatrician, then completes an additional training called a fellowship (for 3 years in the US) in neonatology. Most, but not all neonatologists are board certified in the specialty of Pediatrics by the American Board of Pediatrics, and in the sub-specialty of Neonatal-Perinatal Medicine also by the American Board of Pediatrics. Most countries now run similar programs for fellowship training in Neonatology. Doctorate of Medicine in Neonatology [D.M. (Neonatology)] from India is one such highly regarded program.

 Spectrum of care

Rather focusing on a particular organ system, neonatologists focus on the care of newborns who require ICU hospitalization. They may also act as general pediatricians, providing well newborn evaluation and care in the hospital where they are based. Some neonatologists, particularly those in academic settings, may follow infants for months or even years after hospital discharge to better assess the long term effects of health problems early in life. Some neonatologists perform clinical and basic science research to further our understanding of this special population of patients.

 References

  1. ^ Baines, M.A. (1862). Excessive Infant-Mortality: How Can It Be Stayed?. https://www.neonatology.org/classics/baines.html#note1. Retrieved on 2007-02-18. 
  2. ^ American Academy of Pediatrics (2001). "Committee Report: American Pediatrics: Milestones at the Millennium". Pediatrics 107: 1482–1491. doi:10.1542/peds.107.6.1482. PMID 11389283. 
  3. ^ Lemmons, J.A., et al. (2001). "Very Low Birth Weight Outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 Through December 1996". Pediatrics 107(1): 1–8. doi:10.1542/peds.107.1.e1. PMID 11134465.

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 楼主| 郑振寰 发表于 2010-3-4 12:44 | 显示全部楼层

Incubator (microbiology)

A Bacteriological incubator


In microbiology, an incubator is a device for controlling the temperature, humidity, and other conditions in which a microbiological culture is being grown. The simplest incubators are insulated boxes with an adjustable heater, typically going up to 60 to 65 °C (140 to 150 °F), though some can go slightly higher (generally to no more than 100 °C). More elaborate incubators can also include the ability to lower the temperature (via refrigeration), or the ability to control humidity or CO2 levels.

Most incubators include a timer; some can also be programmed to cycle through different temperatures, humidity levels, etc. Incubators can vary in size from tabletop to units the size of small rooms.

Incubators also contain certain features such as the shake speed, measured by revolutions per minute. As for temperature, most commonly used is approximately 36 to 37 degrees Celsius. Most bacteria, especially the frequently used E. Coli, grow well under such conditions. For other experimental organisms, such as the budding yeast Saccharomyces cerevisiae, a growth temperature of 30 °C is optimal.


 

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 楼主| 郑振寰 发表于 2010-3-4 12:45 | 显示全部楼层

Inkubator

 
Säuglingsinkubator
Inkubator in biotechnologischem Laboratorium

Als Inkubator wird ein Behälter bezeichnet, der in der Regel bei Temperaturen zwischen 4°C und 72°C betrieben wird und für diverse Anwendungen genutzt werden kann. Alternativ werden Inkubatoren auch als Brut- oder Wärmeschrank bezeichnet.

Inkubatoren werden häufig in der Biotechnologie für die Zell- und Gewebekultur sowie für Klonierungs-Experimente eingesetzt, siehe: Inkubator (Biologie). In der Medizin finden sie ebenfalls für diverse Brut- und Wachstumsprozesse sowie der Versorgung von Früh- und Neugeborenen Anwendung, siehe: Inkubator (Medizin). Ein Weiteres Einsatzgebiet von Inkubatoren ist die Geflügelzucht.

Heute sind Inkubatoren meist mit einem elektrischen Edelstahl- Rohrheizkörper, einer Umluftturbine, einem elektronischen Temperaturregler und einem Temperaturbegrenzer ausgestattet. Die Umluftturbine sorgt für eine gleichmäßige Erwärmung und Verteilung der erhitzten Luft im Nutzraum.

Weblinks [Bearbeiten]

 Wiktionary: Inkubator – Bedeutungserklärungen, Wortherkunft, Synonyme, Übersetzungen und Grammatik

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